Dietary fat intake and risk of epithelial ovarian cancer in the European Prospective Investigation into Cancer and Nutrition.
Identifieur interne : 003A36 ( Main/Exploration ); précédent : 003A35; suivant : 003A37Dietary fat intake and risk of epithelial ovarian cancer in the European Prospective Investigation into Cancer and Nutrition.
Auteurs : Melissa A. Merritt [Royaume-Uni] ; Elio Riboli [Royaume-Uni] ; Elisabete Weiderpass [Finlande] ; Konstantinos K. Tsilidis [Royaume-Uni] ; Kim Overvad [Danemark] ; Anne Tj Nneland [Danemark] ; Louise Hansen [Danemark] ; Laure Dossus [France] ; Guy Fagherazzi [France] ; Laura Baglietto [Australie] ; Renée T. Fortner [Allemagne] ; Jennifer Ose [Allemagne] ; Annika Steffen [Allemagne] ; Heiner Boeing [Allemagne] ; Antonia Trichopoulou [Grèce] ; Dimitrios Trichopoulos [États-Unis] ; Pagona Lagiou [Grèce] ; Giovanna Masala [Italie] ; Sabina Sieri [Italie] ; Amalia Mattiello [Italie] ; Rosario Tumino [Italie] ; Carlotta Sacerdote [Italie] ; H B As Bueno-De-Mesquita [Pays-Bas] ; N Charlotte Onland-Moret [Pays-Bas] ; Petra H. Peeters [Pays-Bas] ; Anette Hjart Ker [Norvège] ; Inger Torhild Gram [Norvège] ; J Ram N Quir S [Espagne] ; Mireia Ob N-Santacana [Espagne] ; Esther Molina-Montes [Espagne] ; José María Huerta Casta O [Espagne] ; Eva Ardanaz [Espagne] ; Saioa Chamosa [Espagne] ; Emily Sonestedt [Suède] ; Annika Idahl [Suède] ; Eva Lundin [Suède] ; Kay-Tee Khaw [Royaume-Uni] ; Nicholas Wareham [Royaume-Uni] ; Ruth C. Travis [Royaume-Uni] ; Sabina Rinaldi [France] ; Isabelle Romieu [France] ; Veronique Chajes [France] ; Marc J. Gunter [Royaume-Uni]Source :
- Cancer epidemiology [ 1877-783X ] ; 2014.
Descripteurs français
- KwdFr :
- Adulte, Adulte d'âge moyen, Analyse multivariée, Femelle, Humains, Matières grasses alimentaires (administration et posologie), Matières grasses alimentaires (effets indésirables), Matières grasses alimentaires insaturées (administration et posologie), Matières grasses alimentaires insaturées (effets indésirables), Modèles de hasards proportionnels, Risque, Tumeurs de l'ovaire (épidémiologie), Tumeurs de l'ovaire (étiologie), Tumeurs épithéliales épidermoïdes et glandulaires (épidémiologie), Tumeurs épithéliales épidermoïdes et glandulaires (étiologie), Études de suivi, Études prospectives.
- MESH :
- administration et posologie : Matières grasses alimentaires, Matières grasses alimentaires insaturées.
- effets indésirables : Matières grasses alimentaires, Matières grasses alimentaires insaturées.
- épidémiologie : Tumeurs de l'ovaire, Tumeurs épithéliales épidermoïdes et glandulaires.
- étiologie : Tumeurs de l'ovaire, Tumeurs épithéliales épidermoïdes et glandulaires.
- Adulte, Adulte d'âge moyen, Analyse multivariée, Femelle, Humains, Modèles de hasards proportionnels, Risque, Études de suivi, Études prospectives.
English descriptors
- KwdEn :
- Adult, Dietary Fats (administration & dosage), Dietary Fats (adverse effects), Dietary Fats, Unsaturated (administration & dosage), Dietary Fats, Unsaturated (adverse effects), Female, Follow-Up Studies, Humans, Middle Aged, Multivariate Analysis, Neoplasms, Glandular and Epithelial (epidemiology), Neoplasms, Glandular and Epithelial (etiology), Ovarian Neoplasms (epidemiology), Ovarian Neoplasms (etiology), Proportional Hazards Models, Prospective Studies, Risk.
- MESH :
- chemical , administration & dosage : Dietary Fats, Dietary Fats, Unsaturated.
- chemical , adverse effects : Dietary Fats, Dietary Fats, Unsaturated.
- epidemiology : Neoplasms, Glandular and Epithelial, Ovarian Neoplasms.
- etiology : Neoplasms, Glandular and Epithelial, Ovarian Neoplasms.
- Adult, Female, Follow-Up Studies, Humans, Middle Aged, Multivariate Analysis, Proportional Hazards Models, Prospective Studies, Risk.
Abstract
There are inconsistent and limited data available to assess the relationship between fat intake and risk of epithelial ovarian cancer (EOC). We examined the consumption of total fat, fat sources and fat subtypes in relation to risk of EOC and its major histologic subtypes in the European Prospective Investigation into Cancer and Nutrition which includes incident invasive (n=1095) and borderline (n=96) EOC. Cox proportional hazards regression was used to estimate hazard ratios (HRs) and 95% confidence intervals (CIs). In multivariate models, we observed no association with consumption of total fat, animal or plant fat, saturated fat, cholesterol, monounsaturated fat, or fatty fish and risk of invasive EOC. There was, however, an increased risk of invasive EOC in the highest category of intake (Quartile 4 vs. Quartile 1) of polyunsaturated fat (HR=1.22, 95% CI=1.02-1.48, P(trend)=0.02). We did not observe heterogeneity in the risk associations in comparisons of serous and endometrioid histologic subtypes. This study does not support an etiological role for total fat intake in relation to EOC risk; however, based on observations of a positive association between intake of polyunsaturated fat and invasive EOC risk in the current and previous studies, this fat subtype warrants further investigation to determine its potential role in EOC development.
DOI: 10.1016/j.canep.2014.07.011
PubMed: 25155210
Affiliations:
- Allemagne, Australie, Danemark, Espagne, Finlande, France, Grèce, Italie, Norvège, Pays-Bas, Royaume-Uni, Suède, États-Unis
- Angleterre, Angleterre de l'Est, Bade-Wurtemberg, Catalogne, Communauté de Madrid, District de Karlsruhe, Massachusetts, Oxfordshire, Piémont, Victoria (État), Østlandet
- Barcelone, Cambridge, Heidelberg, Madrid, Melbourne, Oslo, Oxford, Turin
- Université d'Oxford, Université de Cambridge, Université de Melbourne
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Electronic address: m.merritt@imperial.ac.uk.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London, Norfolk Place, London W2 1PG</wicri:regionArea><wicri:noRegion>London W2 1PG</wicri:noRegion></affiliation></author><author><name sortKey="Riboli, Elio" sort="Riboli, Elio" uniqKey="Riboli E" first="Elio" last="Riboli">Elio Riboli</name><affiliation wicri:level="1"><nlm:affiliation>Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London, Norfolk Place, London W2 1PG, United Kingdom.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London, Norfolk Place, London W2 1PG</wicri:regionArea><wicri:noRegion>London W2 1PG</wicri:noRegion></affiliation></author><author><name sortKey="Weiderpass, Elisabete" sort="Weiderpass, Elisabete" uniqKey="Weiderpass E" first="Elisabete" last="Weiderpass">Elisabete Weiderpass</name><affiliation wicri:level="1"><nlm:affiliation>Faculty of Health Sciences, Department of Community Medicine, University of Tromsø, The Arctic University of Norway, N-9037 Tromsø, Norway; Department of Etiological Research, The Cancer Registry of Norway, 0310 Oslo, Norway; Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, PO Box 281, Stockholm 17177, Sweden; Folkhälsan Research Centre, Samfundet Folkhälsan, FI-00290 Helsinki, Finland.</nlm:affiliation><country xml:lang="fr">Finlande</country><wicri:regionArea>Faculty of Health Sciences, Department of Community Medicine, University of Tromsø, The Arctic University of Norway, N-9037 Tromsø, Norway; Department of Etiological Research, The Cancer Registry of Norway, 0310 Oslo, Norway; Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, PO Box 281, Stockholm 17177, Sweden; Folkhälsan Research Centre, Samfundet Folkhälsan, FI-00290 Helsinki</wicri:regionArea><wicri:noRegion>FI-00290 Helsinki</wicri:noRegion></affiliation></author><author><name sortKey="Tsilidis, Konstantinos K" sort="Tsilidis, Konstantinos K" uniqKey="Tsilidis K" first="Konstantinos K" last="Tsilidis">Konstantinos K. Tsilidis</name><affiliation wicri:level="1"><nlm:affiliation>Department of Hygiene and Epidemiology, University of Ioannina School of Medicine, University Campus, 45110 Ioannina, Greece; Cancer Epidemiology Unit, Nuffield Department of Population Health, University of Oxford, Richard Doll Building, Oxford OX3 7LF, United Kingdom.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Department of Hygiene and Epidemiology, University of Ioannina School of Medicine, University Campus, 45110 Ioannina, Greece; Cancer Epidemiology Unit, Nuffield Department of Population Health, University of Oxford, Richard Doll Building, Oxford OX3 7LF</wicri:regionArea><wicri:noRegion>Oxford OX3 7LF</wicri:noRegion></affiliation></author><author><name sortKey="Overvad, Kim" sort="Overvad, Kim" uniqKey="Overvad K" first="Kim" last="Overvad">Kim Overvad</name><affiliation wicri:level="1"><nlm:affiliation>Aarhus University, Department of Public Health, Section for Epidemiology, Bartholins Allé 2 - Building 1260, DK-8000 Aarhus, Denmark.</nlm:affiliation><country xml:lang="fr">Danemark</country><wicri:regionArea>Aarhus University, Department of Public Health, Section for Epidemiology, Bartholins Allé 2 - Building 1260, DK-8000 Aarhus</wicri:regionArea><wicri:noRegion>DK-8000 Aarhus</wicri:noRegion></affiliation></author><author><name sortKey="Tj Nneland, Anne" sort="Tj Nneland, Anne" uniqKey="Tj Nneland A" first="Anne" last="Tj Nneland">Anne Tj Nneland</name><affiliation wicri:level="1"><nlm:affiliation>Danish Cancer Society Research Center, Strandboulevarden 49, DK-2100 Copenhagen, Denmark.</nlm:affiliation><country xml:lang="fr">Danemark</country><wicri:regionArea>Danish Cancer Society Research Center, Strandboulevarden 49, DK-2100 Copenhagen</wicri:regionArea><wicri:noRegion>DK-2100 Copenhagen</wicri:noRegion></affiliation></author><author><name sortKey="Hansen, Louise" sort="Hansen, Louise" uniqKey="Hansen L" first="Louise" last="Hansen">Louise Hansen</name><affiliation wicri:level="1"><nlm:affiliation>Danish Cancer Society Research Center, Strandboulevarden 49, DK-2100 Copenhagen, Denmark.</nlm:affiliation><country xml:lang="fr">Danemark</country><wicri:regionArea>Danish Cancer Society Research Center, Strandboulevarden 49, DK-2100 Copenhagen</wicri:regionArea><wicri:noRegion>DK-2100 Copenhagen</wicri:noRegion></affiliation></author><author><name sortKey="Dossus, Laure" sort="Dossus, Laure" uniqKey="Dossus L" first="Laure" last="Dossus">Laure Dossus</name><affiliation wicri:level="1"><nlm:affiliation>Inserm, Centre for Research in Epidemiology and Population Health (CESP), U1018, Nutrition, Hormones and Women's Health Team, F-94805 Villejuif, France; Univ Paris Sud, UMRS 1018, F-94805 Villejuif, France; Institut Gustave Roussy, F-94805 Villejuif, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>Inserm, Centre for Research in Epidemiology and Population Health (CESP), U1018, Nutrition, Hormones and Women's Health Team, F-94805 Villejuif, France; Univ Paris Sud, UMRS 1018, F-94805 Villejuif, France; Institut Gustave Roussy, F-94805 Villejuif</wicri:regionArea><wicri:noRegion>94805 Villejuif</wicri:noRegion><wicri:noRegion>94805 Villejuif</wicri:noRegion></affiliation></author><author><name sortKey="Fagherazzi, Guy" sort="Fagherazzi, Guy" uniqKey="Fagherazzi G" first="Guy" last="Fagherazzi">Guy Fagherazzi</name><affiliation wicri:level="1"><nlm:affiliation>Inserm, Centre for Research in Epidemiology and Population Health (CESP), U1018, Nutrition, Hormones and Women's Health Team, F-94805 Villejuif, France; Univ Paris Sud, UMRS 1018, F-94805 Villejuif, France; Institut Gustave Roussy, F-94805 Villejuif, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>Inserm, Centre for Research in Epidemiology and Population Health (CESP), U1018, Nutrition, Hormones and Women's Health Team, F-94805 Villejuif, France; Univ Paris Sud, UMRS 1018, F-94805 Villejuif, France; Institut Gustave Roussy, F-94805 Villejuif</wicri:regionArea><wicri:noRegion>94805 Villejuif</wicri:noRegion><wicri:noRegion>94805 Villejuif</wicri:noRegion></affiliation></author><author><name sortKey="Baglietto, Laura" sort="Baglietto, Laura" uniqKey="Baglietto L" first="Laura" last="Baglietto">Laura Baglietto</name><affiliation wicri:level="4"><nlm:affiliation>Cancer Epidemiology Centre, Cancer Council of Victoria, 615 St. Kilda Road, Melbourne, Victoria 3004, Australia; Centre for Epidemiology and Biostatistics, School of Population and Global Health, University of Melbourne, Victoria 3010, Australia.</nlm:affiliation><country xml:lang="fr">Australie</country><wicri:regionArea>Cancer Epidemiology Centre, Cancer Council of Victoria, 615 St. Kilda Road, Melbourne, Victoria 3004, Australia; Centre for Epidemiology and Biostatistics, School of Population and Global Health, University of Melbourne, Victoria 3010</wicri:regionArea><orgName type="university">Université de Melbourne</orgName><placeName><settlement type="city">Melbourne</settlement><region type="état">Victoria (État)</region></placeName></affiliation></author><author><name sortKey="Fortner, Renee T" sort="Fortner, Renee T" uniqKey="Fortner R" first="Renée T" last="Fortner">Renée T. Fortner</name><affiliation wicri:level="3"><nlm:affiliation>Division of Cancer Epidemiology, German Cancer Research Center (DKFZ), Im Neuenheimer Feld 280, 69120 Heidelberg, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Division of Cancer Epidemiology, German Cancer Research Center (DKFZ), Im Neuenheimer Feld 280, 69120 Heidelberg</wicri:regionArea><placeName><region type="land" nuts="1">Bade-Wurtemberg</region><region type="district" nuts="2">District de Karlsruhe</region><settlement type="city">Heidelberg</settlement></placeName></affiliation></author><author><name sortKey="Ose, Jennifer" sort="Ose, Jennifer" uniqKey="Ose J" first="Jennifer" last="Ose">Jennifer Ose</name><affiliation wicri:level="3"><nlm:affiliation>Division of Cancer Epidemiology, German Cancer Research Center (DKFZ), Im Neuenheimer Feld 280, 69120 Heidelberg, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Division of Cancer Epidemiology, German Cancer Research Center (DKFZ), Im Neuenheimer Feld 280, 69120 Heidelberg</wicri:regionArea><placeName><region type="land" nuts="1">Bade-Wurtemberg</region><region type="district" nuts="2">District de Karlsruhe</region><settlement type="city">Heidelberg</settlement></placeName></affiliation></author><author><name sortKey="Steffen, Annika" sort="Steffen, Annika" uniqKey="Steffen A" first="Annika" last="Steffen">Annika Steffen</name><affiliation wicri:level="1"><nlm:affiliation>German Institute of Human Nutrition, Potsdam-Rehbrücke (DIfE), Department of Epidemiology, Arthur-Scheunert-Allee 114-116, 14558 Nuthetal, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>German Institute of Human Nutrition, Potsdam-Rehbrücke (DIfE), Department of Epidemiology, Arthur-Scheunert-Allee 114-116, 14558 Nuthetal</wicri:regionArea><wicri:noRegion>14558 Nuthetal</wicri:noRegion><wicri:noRegion>14558 Nuthetal</wicri:noRegion><wicri:noRegion>14558 Nuthetal</wicri:noRegion></affiliation></author><author><name sortKey="Boeing, Heiner" sort="Boeing, Heiner" uniqKey="Boeing H" first="Heiner" last="Boeing">Heiner Boeing</name><affiliation wicri:level="1"><nlm:affiliation>German Institute of Human Nutrition, Potsdam-Rehbrücke (DIfE), Department of Epidemiology, Arthur-Scheunert-Allee 114-116, 14558 Nuthetal, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>German Institute of Human Nutrition, Potsdam-Rehbrücke (DIfE), Department of Epidemiology, Arthur-Scheunert-Allee 114-116, 14558 Nuthetal</wicri:regionArea><wicri:noRegion>14558 Nuthetal</wicri:noRegion><wicri:noRegion>14558 Nuthetal</wicri:noRegion><wicri:noRegion>14558 Nuthetal</wicri:noRegion></affiliation></author><author><name sortKey="Trichopoulou, Antonia" sort="Trichopoulou, Antonia" uniqKey="Trichopoulou A" first="Antonia" last="Trichopoulou">Antonia Trichopoulou</name><affiliation wicri:level="1"><nlm:affiliation>Hellenic Health Foundation, 13 Kaisareias Street, Athens GR-115 27, Greece; Bureau of Epidemiologic Research, Academy of Athens, 23 Alexandroupoleos Street, Athens GR-115 27, Greece.</nlm:affiliation><country xml:lang="fr">Grèce</country><wicri:regionArea>Hellenic Health Foundation, 13 Kaisareias Street, Athens GR-115 27, Greece; Bureau of Epidemiologic Research, Academy of Athens, 23 Alexandroupoleos Street, Athens GR-115 27</wicri:regionArea><wicri:noRegion>Athens GR-115 27</wicri:noRegion></affiliation></author><author><name sortKey="Trichopoulos, Dimitrios" sort="Trichopoulos, Dimitrios" uniqKey="Trichopoulos D" first="Dimitrios" last="Trichopoulos">Dimitrios Trichopoulos</name><affiliation wicri:level="2"><nlm:affiliation>Hellenic Health Foundation, 13 Kaisareias Street, Athens GR-115 27, Greece; Bureau of Epidemiologic Research, Academy of Athens, 23 Alexandroupoleos Street, Athens GR-115 27, Greece; Department of Epidemiology, Harvard School of Public Health, 677 Huntington Avenue, Boston, MA 02115, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Hellenic Health Foundation, 13 Kaisareias Street, Athens GR-115 27, Greece; Bureau of Epidemiologic Research, Academy of Athens, 23 Alexandroupoleos Street, Athens GR-115 27, Greece; Department of Epidemiology, Harvard School of Public Health, 677 Huntington Avenue, Boston, MA 02115</wicri:regionArea><placeName><region type="state">Massachusetts</region></placeName></affiliation></author><author><name sortKey="Lagiou, Pagona" sort="Lagiou, Pagona" uniqKey="Lagiou P" first="Pagona" last="Lagiou">Pagona Lagiou</name><affiliation wicri:level="1"><nlm:affiliation>Bureau of Epidemiologic Research, Academy of Athens, 23 Alexandroupoleos Street, Athens GR-115 27, Greece; Department of Epidemiology, Harvard School of Public Health, 677 Huntington Avenue, Boston, MA 02115, USA; Department of Hygiene, Epidemiology and Medical Statistics, University of Athens Medical School, Mikras Asias 75, Goudi, GR-115 27 Athens, Greece.</nlm:affiliation><country xml:lang="fr">Grèce</country><wicri:regionArea>Bureau of Epidemiologic Research, Academy of Athens, 23 Alexandroupoleos Street, Athens GR-115 27, Greece; Department of Epidemiology, Harvard School of Public Health, 677 Huntington Avenue, Boston, MA 02115, USA; Department of Hygiene, Epidemiology and Medical Statistics, University of Athens Medical School, Mikras Asias 75, Goudi, GR-115 27 Athens</wicri:regionArea><wicri:noRegion>GR-115 27 Athens</wicri:noRegion></affiliation></author><author><name sortKey="Masala, Giovanna" sort="Masala, Giovanna" uniqKey="Masala G" first="Giovanna" last="Masala">Giovanna Masala</name><affiliation wicri:level="1"><nlm:affiliation>Molecular and Nutritional Epidemiology Unit, Cancer Research and Prevention Institute - ISPO, Ponte Nuovo Palazzina 28 A "Mario Fiori", Via delle Oblate 4, 50141 Florence, Italy.</nlm:affiliation><country xml:lang="fr">Italie</country><wicri:regionArea>Molecular and Nutritional Epidemiology Unit, Cancer Research and Prevention Institute - ISPO, Ponte Nuovo Palazzina 28 A "Mario Fiori", Via delle Oblate 4, 50141 Florence</wicri:regionArea><wicri:noRegion>50141 Florence</wicri:noRegion></affiliation></author><author><name sortKey="Sieri, Sabina" sort="Sieri, Sabina" uniqKey="Sieri S" first="Sabina" last="Sieri">Sabina Sieri</name><affiliation wicri:level="1"><nlm:affiliation>Epidemiology and Prevention Unit, Fondazione IRCCS Istituto Nazionale dei Tumori, Via Venezian, 1, 20133 Milano, Italy.</nlm:affiliation><country xml:lang="fr">Italie</country><wicri:regionArea>Epidemiology and Prevention Unit, Fondazione IRCCS Istituto Nazionale dei Tumori, Via Venezian, 1, 20133 Milano</wicri:regionArea><wicri:noRegion>20133 Milano</wicri:noRegion></affiliation></author><author><name sortKey="Mattiello, Amalia" sort="Mattiello, Amalia" uniqKey="Mattiello A" first="Amalia" last="Mattiello">Amalia Mattiello</name><affiliation wicri:level="1"><nlm:affiliation>Dipartimento di Medicina Clinica e Chirurgia, Federico II University, Corso Umberto I, 40, 80138 Naples, Italy.</nlm:affiliation><country xml:lang="fr">Italie</country><wicri:regionArea>Dipartimento di Medicina Clinica e Chirurgia, Federico II University, Corso Umberto I, 40, 80138 Naples</wicri:regionArea><wicri:noRegion>80138 Naples</wicri:noRegion></affiliation></author><author><name sortKey="Tumino, Rosario" sort="Tumino, Rosario" uniqKey="Tumino R" first="Rosario" last="Tumino">Rosario Tumino</name><affiliation wicri:level="1"><nlm:affiliation>Cancer Registry and Histopathology Unit, "Civic-M.P.Arezzo" Hospital, ASP, Via Dante N° 109, 97100 Ragusa, Italy.</nlm:affiliation><country xml:lang="fr">Italie</country><wicri:regionArea>Cancer Registry and Histopathology Unit, "Civic-M.P.Arezzo" Hospital, ASP, Via Dante N° 109, 97100 Ragusa</wicri:regionArea><wicri:noRegion>97100 Ragusa</wicri:noRegion></affiliation></author><author><name sortKey="Sacerdote, Carlotta" sort="Sacerdote, Carlotta" uniqKey="Sacerdote C" first="Carlotta" last="Sacerdote">Carlotta Sacerdote</name><affiliation wicri:level="1"><nlm:affiliation>Unit of Cancer Epidemiology, AO Citta' della Salute e della Scienza-University of Turin and Center for Cancer Prevention (CPO-Piemonte), Via Santena 7, 10126 Turin, Italy; Human Genetics Foundation (HuGeF), Via Nizza 52, 10126 Turin, Italy.</nlm:affiliation><country xml:lang="fr">Italie</country><wicri:regionArea>Unit of Cancer Epidemiology, AO Citta' della Salute e della Scienza-University of Turin and Center for Cancer Prevention (CPO-Piemonte), Via Santena 7, 10126 Turin, Italy; Human Genetics Foundation (HuGeF), Via Nizza 52, 10126 Turin</wicri:regionArea><placeName><settlement type="city">Turin</settlement><region type="région" nuts="2">Piémont</region></placeName></affiliation></author><author><name sortKey="Bueno De Mesquita, H B As" sort="Bueno De Mesquita, H B As" uniqKey="Bueno De Mesquita H" first="H B As" last="Bueno-De-Mesquita">H B As Bueno-De-Mesquita</name><affiliation wicri:level="1"><nlm:affiliation>Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London, Norfolk Place, London W2 1PG, United Kingdom; National Institute for Public Health and the Environment (RIVM), PO Box 1, 3720 BA Bilthoven, The Netherlands; Department of Gastroenterology and Hepatology, University Medical Centre, Heidelberglann 100, 3584 CX Utrecht, The Netherlands.</nlm:affiliation><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London, Norfolk Place, London W2 1PG, United Kingdom; National Institute for Public Health and the Environment (RIVM), PO Box 1, 3720 BA Bilthoven, The Netherlands; Department of Gastroenterology and Hepatology, University Medical Centre, Heidelberglann 100, 3584 CX Utrecht</wicri:regionArea><wicri:noRegion>3584 CX Utrecht</wicri:noRegion></affiliation></author><author><name sortKey="Onland Moret, N Charlotte" sort="Onland Moret, N Charlotte" uniqKey="Onland Moret N" first="N Charlotte" last="Onland-Moret">N Charlotte Onland-Moret</name><affiliation wicri:level="1"><nlm:affiliation>Department of Epidemiology, Julius Center for Health Sciences and Primary Care, University Medical Center, Huispost Str. 6.131, PO Box 85500, 3508 GA Utrecht, The Netherlands.</nlm:affiliation><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Department of Epidemiology, Julius Center for Health Sciences and Primary Care, University Medical Center, Huispost Str. 6.131, PO Box 85500, 3508 GA Utrecht</wicri:regionArea><wicri:noRegion>3508 GA Utrecht</wicri:noRegion></affiliation></author><author><name sortKey="Peeters, Petra H" sort="Peeters, Petra H" uniqKey="Peeters P" first="Petra H" last="Peeters">Petra H. Peeters</name><affiliation wicri:level="1"><nlm:affiliation>Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London, Norfolk Place, London W2 1PG, United Kingdom; Department of Epidemiology, Julius Center for Health Sciences and Primary Care, University Medical Center, Huispost Str. 6.131, PO Box 85500, 3508 GA Utrecht, The Netherlands.</nlm:affiliation><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London, Norfolk Place, London W2 1PG, United Kingdom; Department of Epidemiology, Julius Center for Health Sciences and Primary Care, University Medical Center, Huispost Str. 6.131, PO Box 85500, 3508 GA Utrecht</wicri:regionArea><wicri:noRegion>3508 GA Utrecht</wicri:noRegion></affiliation></author><author><name sortKey="Hjart Ker, Anette" sort="Hjart Ker, Anette" uniqKey="Hjart Ker A" first="Anette" last="Hjart Ker">Anette Hjart Ker</name><affiliation wicri:level="1"><nlm:affiliation>Department of Nutrition, Institute of Basic Medical Sciences, University of Oslo, Postboks 1046 Blindern, 0317 Oslo, Norway.</nlm:affiliation><country xml:lang="fr">Norvège</country><wicri:regionArea>Department of Nutrition, Institute of Basic Medical Sciences, University of Oslo, Postboks 1046 Blindern, 0317 Oslo</wicri:regionArea><placeName><settlement type="city">Oslo</settlement><region nuts="2">Østlandet</region></placeName></affiliation></author><author><name sortKey="Gram, Inger Torhild" sort="Gram, Inger Torhild" uniqKey="Gram I" first="Inger Torhild" last="Gram">Inger Torhild Gram</name><affiliation wicri:level="1"><nlm:affiliation>Faculty of Health Sciences, Department of Community Medicine, University of Tromsø, The Arctic University of Norway, N-9037 Tromsø, Norway.</nlm:affiliation><country xml:lang="fr">Norvège</country><wicri:regionArea>Faculty of Health Sciences, Department of Community Medicine, University of Tromsø, The Arctic University of Norway, N-9037 Tromsø</wicri:regionArea><wicri:noRegion>N-9037 Tromsø</wicri:noRegion></affiliation></author><author><name sortKey="Quir S, J Ram N" sort="Quir S, J Ram N" uniqKey="Quir S J" first="J Ram N" last="Quir S">J Ram N Quir S</name><affiliation wicri:level="1"><nlm:affiliation>Public Health Directorate, Health and Health Care Services Council, C/ Ciriaco Miguel Virgil no 9, CP 33006 Oviedo, Asturias, Spain.</nlm:affiliation><country xml:lang="fr">Espagne</country><wicri:regionArea>Public Health Directorate, Health and Health Care Services Council, C/ Ciriaco Miguel Virgil no 9, CP 33006 Oviedo, Asturias</wicri:regionArea><wicri:noRegion>Asturias</wicri:noRegion></affiliation></author><author><name sortKey="Ob N Santacana, Mireia" sort="Ob N Santacana, Mireia" uniqKey="Ob N Santacana M" first="Mireia" last="Ob N-Santacana">Mireia Ob N-Santacana</name><affiliation wicri:level="1"><nlm:affiliation>Unit of Nutrition, Environment and Cancer, Cancer Epidemiology Research Program, Bellvitge Biomedical Research Institute (IDIBELL), Catalan Institute of Oncology (ICO), Avda Gran Via 199-203, L'Hospitalet del Llobregat, 08907 Barcelona, Spain.</nlm:affiliation><country xml:lang="fr">Espagne</country><wicri:regionArea>Unit of Nutrition, Environment and Cancer, Cancer Epidemiology Research Program, Bellvitge Biomedical Research Institute (IDIBELL), Catalan Institute of Oncology (ICO), Avda Gran Via 199-203, L'Hospitalet del Llobregat, 08907 Barcelona</wicri:regionArea><placeName><settlement type="city">Barcelone</settlement><region nuts="2" type="region">Catalogne</region></placeName></affiliation></author><author><name sortKey="Molina Montes, Esther" sort="Molina Montes, Esther" uniqKey="Molina Montes E" first="Esther" last="Molina-Montes">Esther Molina-Montes</name><affiliation wicri:level="1"><nlm:affiliation>Escuela Andaluza de Salud Pública, Instituto de Investigación Biosanitaria de Granada (Granada.ibs), Cuesta del Observatorio, 4, Campus Universitario de Cartuja, 18080 Granada, Spain; CIBER de Epidemiología y Salud Pública (CIBERESP), Melchor Fernández Almagro, 3-5, 28029 Madrid, Spain.</nlm:affiliation><country xml:lang="fr">Espagne</country><wicri:regionArea>Escuela Andaluza de Salud Pública, Instituto de Investigación Biosanitaria de Granada (Granada.ibs), Cuesta del Observatorio, 4, Campus Universitario de Cartuja, 18080 Granada, Spain; CIBER de Epidemiología y Salud Pública (CIBERESP), Melchor Fernández Almagro, 3-5, 28029 Madrid</wicri:regionArea><placeName><settlement type="city">Madrid</settlement><region nuts="2" type="region">Communauté de Madrid</region></placeName></affiliation></author><author><name sortKey="Huerta Casta O, Jose Maria" sort="Huerta Casta O, Jose Maria" uniqKey="Huerta Casta O J" first="José María" last="Huerta Casta O">José María Huerta Casta O</name><affiliation wicri:level="1"><nlm:affiliation>CIBER de Epidemiología y Salud Pública (CIBERESP), Melchor Fernández Almagro, 3-5, 28029 Madrid, Spain; Department of Epidemiology, Murcia Regional Health Council, Ronda de Levante 11, 30008 Murcia, Spain.</nlm:affiliation><country xml:lang="fr">Espagne</country><wicri:regionArea>CIBER de Epidemiología y Salud Pública (CIBERESP), Melchor Fernández Almagro, 3-5, 28029 Madrid, Spain; Department of Epidemiology, Murcia Regional Health Council, Ronda de Levante 11, 30008 Murcia</wicri:regionArea><wicri:noRegion>30008 Murcia</wicri:noRegion></affiliation></author><author><name sortKey="Ardanaz, Eva" sort="Ardanaz, Eva" uniqKey="Ardanaz E" first="Eva" last="Ardanaz">Eva Ardanaz</name><affiliation wicri:level="1"><nlm:affiliation>CIBER de Epidemiología y Salud Pública (CIBERESP), Melchor Fernández Almagro, 3-5, 28029 Madrid, Spain; Navarre Public Health Institute, Leyre 15, 31003 Pamplona, Spain.</nlm:affiliation><country xml:lang="fr">Espagne</country><wicri:regionArea>CIBER de Epidemiología y Salud Pública (CIBERESP), Melchor Fernández Almagro, 3-5, 28029 Madrid, Spain; Navarre Public Health Institute, Leyre 15, 31003 Pamplona</wicri:regionArea><wicri:noRegion>31003 Pamplona</wicri:noRegion></affiliation></author><author><name sortKey="Chamosa, Saioa" sort="Chamosa, Saioa" uniqKey="Chamosa S" first="Saioa" last="Chamosa">Saioa Chamosa</name><affiliation wicri:level="1"><nlm:affiliation>Public Health Division of Gipuzkoa, BioDonostia Research Institute, Health Department of Basque Region, Avenida de Navarra, 4-20013 Donostia, San Sebastian, Spain.</nlm:affiliation><country xml:lang="fr">Espagne</country><wicri:regionArea>Public Health Division of Gipuzkoa, BioDonostia Research Institute, Health Department of Basque Region, Avenida de Navarra, 4-20013 Donostia, San Sebastian</wicri:regionArea><wicri:noRegion>San Sebastian</wicri:noRegion></affiliation></author><author><name sortKey="Sonestedt, Emily" sort="Sonestedt, Emily" uniqKey="Sonestedt E" first="Emily" last="Sonestedt">Emily Sonestedt</name><affiliation wicri:level="1"><nlm:affiliation>Department of Clinical Sciences in Malmö, Lund University, 20502 Malmö, Sweden.</nlm:affiliation><country xml:lang="fr">Suède</country><wicri:regionArea>Department of Clinical Sciences in Malmö, Lund University, 20502 Malmö</wicri:regionArea><wicri:noRegion>20502 Malmö</wicri:noRegion></affiliation></author><author><name sortKey="Idahl, Annika" sort="Idahl, Annika" uniqKey="Idahl A" first="Annika" last="Idahl">Annika Idahl</name><affiliation wicri:level="1"><nlm:affiliation>Department of Clinical Sciences, Obstetrics and Gynecology, Umeå University, SE-901 87 Umeå, Sweden; Department of Public Health and Clinical Medicine, Nutritional Research, Umeå University, SE-901 87 Umeå, Sweden.</nlm:affiliation><country xml:lang="fr">Suède</country><wicri:regionArea>Department of Clinical Sciences, Obstetrics and Gynecology, Umeå University, SE-901 87 Umeå, Sweden; Department of Public Health and Clinical Medicine, Nutritional Research, Umeå University, SE-901 87 Umeå</wicri:regionArea><wicri:noRegion>SE-901 87 Umeå</wicri:noRegion></affiliation></author><author><name sortKey="Lundin, Eva" sort="Lundin, Eva" uniqKey="Lundin E" first="Eva" last="Lundin">Eva Lundin</name><affiliation wicri:level="1"><nlm:affiliation>Department of Medical Biosciences, Pathology, Umeå University, SE-901 87 Umeå, Sweden.</nlm:affiliation><country xml:lang="fr">Suède</country><wicri:regionArea>Department of Medical Biosciences, Pathology, Umeå University, SE-901 87 Umeå</wicri:regionArea><wicri:noRegion>SE-901 87 Umeå</wicri:noRegion></affiliation></author><author><name sortKey="Khaw, Kay Tee" sort="Khaw, Kay Tee" uniqKey="Khaw K" first="Kay-Tee" last="Khaw">Kay-Tee Khaw</name><affiliation wicri:level="4"><nlm:affiliation>University of Cambridge, School of Clinical Medicine, Addenbrooke's Hospital, Hills Road, Cambridge CB2 0SP, United Kingdom.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>University of Cambridge, School of Clinical Medicine, Addenbrooke's Hospital, Hills Road, Cambridge CB2 0SP</wicri:regionArea><orgName type="university">Université de Cambridge</orgName><placeName><settlement type="city">Cambridge</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Angleterre de l'Est</region></placeName></affiliation></author><author><name sortKey="Wareham, Nicholas" sort="Wareham, Nicholas" uniqKey="Wareham N" first="Nicholas" last="Wareham">Nicholas Wareham</name><affiliation wicri:level="4"><nlm:affiliation>MRC Epidemiology Unit, University of Cambridge, Institute of Metabolic Science, PO Box 285, Addenbrooke's Hospital, Hills Road, Cambridge CB2 0QQ, United Kingdom.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>MRC Epidemiology Unit, University of Cambridge, Institute of Metabolic Science, PO Box 285, Addenbrooke's Hospital, Hills Road, Cambridge CB2 0QQ</wicri:regionArea><orgName type="university">Université de Cambridge</orgName><placeName><settlement type="city">Cambridge</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Angleterre de l'Est</region></placeName></affiliation></author><author><name sortKey="Travis, Ruth C" sort="Travis, Ruth C" uniqKey="Travis R" first="Ruth C" last="Travis">Ruth C. Travis</name><affiliation wicri:level="4"><nlm:affiliation>Cancer Epidemiology Unit, Nuffield Department of Population Health, University of Oxford, Richard Doll Building, Oxford OX3 7LF, United Kingdom.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Cancer Epidemiology Unit, Nuffield Department of Population Health, University of Oxford, Richard Doll Building, Oxford OX3 7LF</wicri:regionArea><orgName type="university">Université d'Oxford</orgName><placeName><settlement type="city">Oxford</settlement><region type="nation">Angleterre</region><region type="région" nuts="1">Oxfordshire</region></placeName></affiliation></author><author><name sortKey="Rinaldi, Sabina" sort="Rinaldi, Sabina" uniqKey="Rinaldi S" first="Sabina" last="Rinaldi">Sabina Rinaldi</name><affiliation wicri:level="1"><nlm:affiliation>International Agency for Research on Cancer, 150 Cours Albert-Thomas, 69372 Lyon Cedex 08, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>International Agency for Research on Cancer, 150 Cours Albert-Thomas, 69372 Lyon Cedex 08</wicri:regionArea><wicri:noRegion>69372 Lyon Cedex 08</wicri:noRegion><wicri:noRegion>69372 Lyon Cedex 08</wicri:noRegion></affiliation></author><author><name sortKey="Romieu, Isabelle" sort="Romieu, Isabelle" uniqKey="Romieu I" first="Isabelle" last="Romieu">Isabelle Romieu</name><affiliation wicri:level="1"><nlm:affiliation>International Agency for Research on Cancer, 150 Cours Albert-Thomas, 69372 Lyon Cedex 08, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>International Agency for Research on Cancer, 150 Cours Albert-Thomas, 69372 Lyon Cedex 08</wicri:regionArea><wicri:noRegion>69372 Lyon Cedex 08</wicri:noRegion><wicri:noRegion>69372 Lyon Cedex 08</wicri:noRegion></affiliation></author><author><name sortKey="Chajes, Veronique" sort="Chajes, Veronique" uniqKey="Chajes V" first="Veronique" last="Chajes">Veronique Chajes</name><affiliation wicri:level="1"><nlm:affiliation>International Agency for Research on Cancer, 150 Cours Albert-Thomas, 69372 Lyon Cedex 08, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>International Agency for Research on Cancer, 150 Cours Albert-Thomas, 69372 Lyon Cedex 08</wicri:regionArea><wicri:noRegion>69372 Lyon Cedex 08</wicri:noRegion><wicri:noRegion>69372 Lyon Cedex 08</wicri:noRegion></affiliation></author><author><name sortKey="Gunter, Marc J" sort="Gunter, Marc J" uniqKey="Gunter M" first="Marc J" last="Gunter">Marc J. Gunter</name><affiliation wicri:level="1"><nlm:affiliation>Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London, Norfolk Place, London W2 1PG, United Kingdom.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London, Norfolk Place, London W2 1PG</wicri:regionArea><wicri:noRegion>London W2 1PG</wicri:noRegion></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">PubMed</idno><date when="2014">2014</date><idno type="RBID">pubmed:25155210</idno><idno type="pmid">25155210</idno><idno type="doi">10.1016/j.canep.2014.07.011</idno><idno type="wicri:Area/PubMed/Corpus">003435</idno><idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Corpus" wicri:corpus="PubMed">003435</idno><idno type="wicri:Area/PubMed/Curation">003322</idno><idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Curation">003322</idno><idno type="wicri:Area/PubMed/Checkpoint">003322</idno><idno type="wicri:explorRef" wicri:stream="Checkpoint" wicri:step="PubMed">003322</idno><idno type="wicri:Area/Ncbi/Merge">001D42</idno><idno type="wicri:Area/Ncbi/Curation">001D42</idno><idno type="wicri:Area/Ncbi/Checkpoint">001D42</idno><idno type="wicri:Area/Main/Merge">003A79</idno><idno type="wicri:Area/Main/Curation">003A36</idno><idno type="wicri:Area/Main/Exploration">003A36</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en">Dietary fat intake and risk of epithelial ovarian cancer in the European Prospective Investigation into Cancer and Nutrition.</title><author><name sortKey="Merritt, Melissa A" sort="Merritt, Melissa A" uniqKey="Merritt M" first="Melissa A" last="Merritt">Melissa A. Merritt</name><affiliation wicri:level="1"><nlm:affiliation>Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London, Norfolk Place, London W2 1PG, United Kingdom. Electronic address: m.merritt@imperial.ac.uk.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London, Norfolk Place, London W2 1PG</wicri:regionArea><wicri:noRegion>London W2 1PG</wicri:noRegion></affiliation></author><author><name sortKey="Riboli, Elio" sort="Riboli, Elio" uniqKey="Riboli E" first="Elio" last="Riboli">Elio Riboli</name><affiliation wicri:level="1"><nlm:affiliation>Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London, Norfolk Place, London W2 1PG, United Kingdom.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London, Norfolk Place, London W2 1PG</wicri:regionArea><wicri:noRegion>London W2 1PG</wicri:noRegion></affiliation></author><author><name sortKey="Weiderpass, Elisabete" sort="Weiderpass, Elisabete" uniqKey="Weiderpass E" first="Elisabete" last="Weiderpass">Elisabete Weiderpass</name><affiliation wicri:level="1"><nlm:affiliation>Faculty of Health Sciences, Department of Community Medicine, University of Tromsø, The Arctic University of Norway, N-9037 Tromsø, Norway; Department of Etiological Research, The Cancer Registry of Norway, 0310 Oslo, Norway; Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, PO Box 281, Stockholm 17177, Sweden; Folkhälsan Research Centre, Samfundet Folkhälsan, FI-00290 Helsinki, Finland.</nlm:affiliation><country xml:lang="fr">Finlande</country><wicri:regionArea>Faculty of Health Sciences, Department of Community Medicine, University of Tromsø, The Arctic University of Norway, N-9037 Tromsø, Norway; Department of Etiological Research, The Cancer Registry of Norway, 0310 Oslo, Norway; Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, PO Box 281, Stockholm 17177, Sweden; Folkhälsan Research Centre, Samfundet Folkhälsan, FI-00290 Helsinki</wicri:regionArea><wicri:noRegion>FI-00290 Helsinki</wicri:noRegion></affiliation></author><author><name sortKey="Tsilidis, Konstantinos K" sort="Tsilidis, Konstantinos K" uniqKey="Tsilidis K" first="Konstantinos K" last="Tsilidis">Konstantinos K. Tsilidis</name><affiliation wicri:level="1"><nlm:affiliation>Department of Hygiene and Epidemiology, University of Ioannina School of Medicine, University Campus, 45110 Ioannina, Greece; Cancer Epidemiology Unit, Nuffield Department of Population Health, University of Oxford, Richard Doll Building, Oxford OX3 7LF, United Kingdom.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Department of Hygiene and Epidemiology, University of Ioannina School of Medicine, University Campus, 45110 Ioannina, Greece; Cancer Epidemiology Unit, Nuffield Department of Population Health, University of Oxford, Richard Doll Building, Oxford OX3 7LF</wicri:regionArea><wicri:noRegion>Oxford OX3 7LF</wicri:noRegion></affiliation></author><author><name sortKey="Overvad, Kim" sort="Overvad, Kim" uniqKey="Overvad K" first="Kim" last="Overvad">Kim Overvad</name><affiliation wicri:level="1"><nlm:affiliation>Aarhus University, Department of Public Health, Section for Epidemiology, Bartholins Allé 2 - Building 1260, DK-8000 Aarhus, Denmark.</nlm:affiliation><country xml:lang="fr">Danemark</country><wicri:regionArea>Aarhus University, Department of Public Health, Section for Epidemiology, Bartholins Allé 2 - Building 1260, DK-8000 Aarhus</wicri:regionArea><wicri:noRegion>DK-8000 Aarhus</wicri:noRegion></affiliation></author><author><name sortKey="Tj Nneland, Anne" sort="Tj Nneland, Anne" uniqKey="Tj Nneland A" first="Anne" last="Tj Nneland">Anne Tj Nneland</name><affiliation wicri:level="1"><nlm:affiliation>Danish Cancer Society Research Center, Strandboulevarden 49, DK-2100 Copenhagen, Denmark.</nlm:affiliation><country xml:lang="fr">Danemark</country><wicri:regionArea>Danish Cancer Society Research Center, Strandboulevarden 49, DK-2100 Copenhagen</wicri:regionArea><wicri:noRegion>DK-2100 Copenhagen</wicri:noRegion></affiliation></author><author><name sortKey="Hansen, Louise" sort="Hansen, Louise" uniqKey="Hansen L" first="Louise" last="Hansen">Louise Hansen</name><affiliation wicri:level="1"><nlm:affiliation>Danish Cancer Society Research Center, Strandboulevarden 49, DK-2100 Copenhagen, Denmark.</nlm:affiliation><country xml:lang="fr">Danemark</country><wicri:regionArea>Danish Cancer Society Research Center, Strandboulevarden 49, DK-2100 Copenhagen</wicri:regionArea><wicri:noRegion>DK-2100 Copenhagen</wicri:noRegion></affiliation></author><author><name sortKey="Dossus, Laure" sort="Dossus, Laure" uniqKey="Dossus L" first="Laure" last="Dossus">Laure Dossus</name><affiliation wicri:level="1"><nlm:affiliation>Inserm, Centre for Research in Epidemiology and Population Health (CESP), U1018, Nutrition, Hormones and Women's Health Team, F-94805 Villejuif, France; Univ Paris Sud, UMRS 1018, F-94805 Villejuif, France; Institut Gustave Roussy, F-94805 Villejuif, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>Inserm, Centre for Research in Epidemiology and Population Health (CESP), U1018, Nutrition, Hormones and Women's Health Team, F-94805 Villejuif, France; Univ Paris Sud, UMRS 1018, F-94805 Villejuif, France; Institut Gustave Roussy, F-94805 Villejuif</wicri:regionArea><wicri:noRegion>94805 Villejuif</wicri:noRegion><wicri:noRegion>94805 Villejuif</wicri:noRegion></affiliation></author><author><name sortKey="Fagherazzi, Guy" sort="Fagherazzi, Guy" uniqKey="Fagherazzi G" first="Guy" last="Fagherazzi">Guy Fagherazzi</name><affiliation wicri:level="1"><nlm:affiliation>Inserm, Centre for Research in Epidemiology and Population Health (CESP), U1018, Nutrition, Hormones and Women's Health Team, F-94805 Villejuif, France; Univ Paris Sud, UMRS 1018, F-94805 Villejuif, France; Institut Gustave Roussy, F-94805 Villejuif, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>Inserm, Centre for Research in Epidemiology and Population Health (CESP), U1018, Nutrition, Hormones and Women's Health Team, F-94805 Villejuif, France; Univ Paris Sud, UMRS 1018, F-94805 Villejuif, France; Institut Gustave Roussy, F-94805 Villejuif</wicri:regionArea><wicri:noRegion>94805 Villejuif</wicri:noRegion><wicri:noRegion>94805 Villejuif</wicri:noRegion></affiliation></author><author><name sortKey="Baglietto, Laura" sort="Baglietto, Laura" uniqKey="Baglietto L" first="Laura" last="Baglietto">Laura Baglietto</name><affiliation wicri:level="4"><nlm:affiliation>Cancer Epidemiology Centre, Cancer Council of Victoria, 615 St. Kilda Road, Melbourne, Victoria 3004, Australia; Centre for Epidemiology and Biostatistics, School of Population and Global Health, University of Melbourne, Victoria 3010, Australia.</nlm:affiliation><country xml:lang="fr">Australie</country><wicri:regionArea>Cancer Epidemiology Centre, Cancer Council of Victoria, 615 St. Kilda Road, Melbourne, Victoria 3004, Australia; Centre for Epidemiology and Biostatistics, School of Population and Global Health, University of Melbourne, Victoria 3010</wicri:regionArea><orgName type="university">Université de Melbourne</orgName><placeName><settlement type="city">Melbourne</settlement><region type="état">Victoria (État)</region></placeName></affiliation></author><author><name sortKey="Fortner, Renee T" sort="Fortner, Renee T" uniqKey="Fortner R" first="Renée T" last="Fortner">Renée T. Fortner</name><affiliation wicri:level="3"><nlm:affiliation>Division of Cancer Epidemiology, German Cancer Research Center (DKFZ), Im Neuenheimer Feld 280, 69120 Heidelberg, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Division of Cancer Epidemiology, German Cancer Research Center (DKFZ), Im Neuenheimer Feld 280, 69120 Heidelberg</wicri:regionArea><placeName><region type="land" nuts="1">Bade-Wurtemberg</region><region type="district" nuts="2">District de Karlsruhe</region><settlement type="city">Heidelberg</settlement></placeName></affiliation></author><author><name sortKey="Ose, Jennifer" sort="Ose, Jennifer" uniqKey="Ose J" first="Jennifer" last="Ose">Jennifer Ose</name><affiliation wicri:level="3"><nlm:affiliation>Division of Cancer Epidemiology, German Cancer Research Center (DKFZ), Im Neuenheimer Feld 280, 69120 Heidelberg, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>Division of Cancer Epidemiology, German Cancer Research Center (DKFZ), Im Neuenheimer Feld 280, 69120 Heidelberg</wicri:regionArea><placeName><region type="land" nuts="1">Bade-Wurtemberg</region><region type="district" nuts="2">District de Karlsruhe</region><settlement type="city">Heidelberg</settlement></placeName></affiliation></author><author><name sortKey="Steffen, Annika" sort="Steffen, Annika" uniqKey="Steffen A" first="Annika" last="Steffen">Annika Steffen</name><affiliation wicri:level="1"><nlm:affiliation>German Institute of Human Nutrition, Potsdam-Rehbrücke (DIfE), Department of Epidemiology, Arthur-Scheunert-Allee 114-116, 14558 Nuthetal, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>German Institute of Human Nutrition, Potsdam-Rehbrücke (DIfE), Department of Epidemiology, Arthur-Scheunert-Allee 114-116, 14558 Nuthetal</wicri:regionArea><wicri:noRegion>14558 Nuthetal</wicri:noRegion><wicri:noRegion>14558 Nuthetal</wicri:noRegion><wicri:noRegion>14558 Nuthetal</wicri:noRegion></affiliation></author><author><name sortKey="Boeing, Heiner" sort="Boeing, Heiner" uniqKey="Boeing H" first="Heiner" last="Boeing">Heiner Boeing</name><affiliation wicri:level="1"><nlm:affiliation>German Institute of Human Nutrition, Potsdam-Rehbrücke (DIfE), Department of Epidemiology, Arthur-Scheunert-Allee 114-116, 14558 Nuthetal, Germany.</nlm:affiliation><country xml:lang="fr">Allemagne</country><wicri:regionArea>German Institute of Human Nutrition, Potsdam-Rehbrücke (DIfE), Department of Epidemiology, Arthur-Scheunert-Allee 114-116, 14558 Nuthetal</wicri:regionArea><wicri:noRegion>14558 Nuthetal</wicri:noRegion><wicri:noRegion>14558 Nuthetal</wicri:noRegion><wicri:noRegion>14558 Nuthetal</wicri:noRegion></affiliation></author><author><name sortKey="Trichopoulou, Antonia" sort="Trichopoulou, Antonia" uniqKey="Trichopoulou A" first="Antonia" last="Trichopoulou">Antonia Trichopoulou</name><affiliation wicri:level="1"><nlm:affiliation>Hellenic Health Foundation, 13 Kaisareias Street, Athens GR-115 27, Greece; Bureau of Epidemiologic Research, Academy of Athens, 23 Alexandroupoleos Street, Athens GR-115 27, Greece.</nlm:affiliation><country xml:lang="fr">Grèce</country><wicri:regionArea>Hellenic Health Foundation, 13 Kaisareias Street, Athens GR-115 27, Greece; Bureau of Epidemiologic Research, Academy of Athens, 23 Alexandroupoleos Street, Athens GR-115 27</wicri:regionArea><wicri:noRegion>Athens GR-115 27</wicri:noRegion></affiliation></author><author><name sortKey="Trichopoulos, Dimitrios" sort="Trichopoulos, Dimitrios" uniqKey="Trichopoulos D" first="Dimitrios" last="Trichopoulos">Dimitrios Trichopoulos</name><affiliation wicri:level="2"><nlm:affiliation>Hellenic Health Foundation, 13 Kaisareias Street, Athens GR-115 27, Greece; Bureau of Epidemiologic Research, Academy of Athens, 23 Alexandroupoleos Street, Athens GR-115 27, Greece; Department of Epidemiology, Harvard School of Public Health, 677 Huntington Avenue, Boston, MA 02115, USA.</nlm:affiliation><country xml:lang="fr">États-Unis</country><wicri:regionArea>Hellenic Health Foundation, 13 Kaisareias Street, Athens GR-115 27, Greece; Bureau of Epidemiologic Research, Academy of Athens, 23 Alexandroupoleos Street, Athens GR-115 27, Greece; Department of Epidemiology, Harvard School of Public Health, 677 Huntington Avenue, Boston, MA 02115</wicri:regionArea><placeName><region type="state">Massachusetts</region></placeName></affiliation></author><author><name sortKey="Lagiou, Pagona" sort="Lagiou, Pagona" uniqKey="Lagiou P" first="Pagona" last="Lagiou">Pagona Lagiou</name><affiliation wicri:level="1"><nlm:affiliation>Bureau of Epidemiologic Research, Academy of Athens, 23 Alexandroupoleos Street, Athens GR-115 27, Greece; Department of Epidemiology, Harvard School of Public Health, 677 Huntington Avenue, Boston, MA 02115, USA; Department of Hygiene, Epidemiology and Medical Statistics, University of Athens Medical School, Mikras Asias 75, Goudi, GR-115 27 Athens, Greece.</nlm:affiliation><country xml:lang="fr">Grèce</country><wicri:regionArea>Bureau of Epidemiologic Research, Academy of Athens, 23 Alexandroupoleos Street, Athens GR-115 27, Greece; Department of Epidemiology, Harvard School of Public Health, 677 Huntington Avenue, Boston, MA 02115, USA; Department of Hygiene, Epidemiology and Medical Statistics, University of Athens Medical School, Mikras Asias 75, Goudi, GR-115 27 Athens</wicri:regionArea><wicri:noRegion>GR-115 27 Athens</wicri:noRegion></affiliation></author><author><name sortKey="Masala, Giovanna" sort="Masala, Giovanna" uniqKey="Masala G" first="Giovanna" last="Masala">Giovanna Masala</name><affiliation wicri:level="1"><nlm:affiliation>Molecular and Nutritional Epidemiology Unit, Cancer Research and Prevention Institute - ISPO, Ponte Nuovo Palazzina 28 A "Mario Fiori", Via delle Oblate 4, 50141 Florence, Italy.</nlm:affiliation><country xml:lang="fr">Italie</country><wicri:regionArea>Molecular and Nutritional Epidemiology Unit, Cancer Research and Prevention Institute - ISPO, Ponte Nuovo Palazzina 28 A "Mario Fiori", Via delle Oblate 4, 50141 Florence</wicri:regionArea><wicri:noRegion>50141 Florence</wicri:noRegion></affiliation></author><author><name sortKey="Sieri, Sabina" sort="Sieri, Sabina" uniqKey="Sieri S" first="Sabina" last="Sieri">Sabina Sieri</name><affiliation wicri:level="1"><nlm:affiliation>Epidemiology and Prevention Unit, Fondazione IRCCS Istituto Nazionale dei Tumori, Via Venezian, 1, 20133 Milano, Italy.</nlm:affiliation><country xml:lang="fr">Italie</country><wicri:regionArea>Epidemiology and Prevention Unit, Fondazione IRCCS Istituto Nazionale dei Tumori, Via Venezian, 1, 20133 Milano</wicri:regionArea><wicri:noRegion>20133 Milano</wicri:noRegion></affiliation></author><author><name sortKey="Mattiello, Amalia" sort="Mattiello, Amalia" uniqKey="Mattiello A" first="Amalia" last="Mattiello">Amalia Mattiello</name><affiliation wicri:level="1"><nlm:affiliation>Dipartimento di Medicina Clinica e Chirurgia, Federico II University, Corso Umberto I, 40, 80138 Naples, Italy.</nlm:affiliation><country xml:lang="fr">Italie</country><wicri:regionArea>Dipartimento di Medicina Clinica e Chirurgia, Federico II University, Corso Umberto I, 40, 80138 Naples</wicri:regionArea><wicri:noRegion>80138 Naples</wicri:noRegion></affiliation></author><author><name sortKey="Tumino, Rosario" sort="Tumino, Rosario" uniqKey="Tumino R" first="Rosario" last="Tumino">Rosario Tumino</name><affiliation wicri:level="1"><nlm:affiliation>Cancer Registry and Histopathology Unit, "Civic-M.P.Arezzo" Hospital, ASP, Via Dante N° 109, 97100 Ragusa, Italy.</nlm:affiliation><country xml:lang="fr">Italie</country><wicri:regionArea>Cancer Registry and Histopathology Unit, "Civic-M.P.Arezzo" Hospital, ASP, Via Dante N° 109, 97100 Ragusa</wicri:regionArea><wicri:noRegion>97100 Ragusa</wicri:noRegion></affiliation></author><author><name sortKey="Sacerdote, Carlotta" sort="Sacerdote, Carlotta" uniqKey="Sacerdote C" first="Carlotta" last="Sacerdote">Carlotta Sacerdote</name><affiliation wicri:level="1"><nlm:affiliation>Unit of Cancer Epidemiology, AO Citta' della Salute e della Scienza-University of Turin and Center for Cancer Prevention (CPO-Piemonte), Via Santena 7, 10126 Turin, Italy; Human Genetics Foundation (HuGeF), Via Nizza 52, 10126 Turin, Italy.</nlm:affiliation><country xml:lang="fr">Italie</country><wicri:regionArea>Unit of Cancer Epidemiology, AO Citta' della Salute e della Scienza-University of Turin and Center for Cancer Prevention (CPO-Piemonte), Via Santena 7, 10126 Turin, Italy; Human Genetics Foundation (HuGeF), Via Nizza 52, 10126 Turin</wicri:regionArea><placeName><settlement type="city">Turin</settlement><region type="région" nuts="2">Piémont</region></placeName></affiliation></author><author><name sortKey="Bueno De Mesquita, H B As" sort="Bueno De Mesquita, H B As" uniqKey="Bueno De Mesquita H" first="H B As" last="Bueno-De-Mesquita">H B As Bueno-De-Mesquita</name><affiliation wicri:level="1"><nlm:affiliation>Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London, Norfolk Place, London W2 1PG, United Kingdom; National Institute for Public Health and the Environment (RIVM), PO Box 1, 3720 BA Bilthoven, The Netherlands; Department of Gastroenterology and Hepatology, University Medical Centre, Heidelberglann 100, 3584 CX Utrecht, The Netherlands.</nlm:affiliation><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London, Norfolk Place, London W2 1PG, United Kingdom; National Institute for Public Health and the Environment (RIVM), PO Box 1, 3720 BA Bilthoven, The Netherlands; Department of Gastroenterology and Hepatology, University Medical Centre, Heidelberglann 100, 3584 CX Utrecht</wicri:regionArea><wicri:noRegion>3584 CX Utrecht</wicri:noRegion></affiliation></author><author><name sortKey="Onland Moret, N Charlotte" sort="Onland Moret, N Charlotte" uniqKey="Onland Moret N" first="N Charlotte" last="Onland-Moret">N Charlotte Onland-Moret</name><affiliation wicri:level="1"><nlm:affiliation>Department of Epidemiology, Julius Center for Health Sciences and Primary Care, University Medical Center, Huispost Str. 6.131, PO Box 85500, 3508 GA Utrecht, The Netherlands.</nlm:affiliation><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Department of Epidemiology, Julius Center for Health Sciences and Primary Care, University Medical Center, Huispost Str. 6.131, PO Box 85500, 3508 GA Utrecht</wicri:regionArea><wicri:noRegion>3508 GA Utrecht</wicri:noRegion></affiliation></author><author><name sortKey="Peeters, Petra H" sort="Peeters, Petra H" uniqKey="Peeters P" first="Petra H" last="Peeters">Petra H. Peeters</name><affiliation wicri:level="1"><nlm:affiliation>Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London, Norfolk Place, London W2 1PG, United Kingdom; Department of Epidemiology, Julius Center for Health Sciences and Primary Care, University Medical Center, Huispost Str. 6.131, PO Box 85500, 3508 GA Utrecht, The Netherlands.</nlm:affiliation><country xml:lang="fr">Pays-Bas</country><wicri:regionArea>Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London, Norfolk Place, London W2 1PG, United Kingdom; Department of Epidemiology, Julius Center for Health Sciences and Primary Care, University Medical Center, Huispost Str. 6.131, PO Box 85500, 3508 GA Utrecht</wicri:regionArea><wicri:noRegion>3508 GA Utrecht</wicri:noRegion></affiliation></author><author><name sortKey="Hjart Ker, Anette" sort="Hjart Ker, Anette" uniqKey="Hjart Ker A" first="Anette" last="Hjart Ker">Anette Hjart Ker</name><affiliation wicri:level="1"><nlm:affiliation>Department of Nutrition, Institute of Basic Medical Sciences, University of Oslo, Postboks 1046 Blindern, 0317 Oslo, Norway.</nlm:affiliation><country xml:lang="fr">Norvège</country><wicri:regionArea>Department of Nutrition, Institute of Basic Medical Sciences, University of Oslo, Postboks 1046 Blindern, 0317 Oslo</wicri:regionArea><placeName><settlement type="city">Oslo</settlement><region nuts="2">Østlandet</region></placeName></affiliation></author><author><name sortKey="Gram, Inger Torhild" sort="Gram, Inger Torhild" uniqKey="Gram I" first="Inger Torhild" last="Gram">Inger Torhild Gram</name><affiliation wicri:level="1"><nlm:affiliation>Faculty of Health Sciences, Department of Community Medicine, University of Tromsø, The Arctic University of Norway, N-9037 Tromsø, Norway.</nlm:affiliation><country xml:lang="fr">Norvège</country><wicri:regionArea>Faculty of Health Sciences, Department of Community Medicine, University of Tromsø, The Arctic University of Norway, N-9037 Tromsø</wicri:regionArea><wicri:noRegion>N-9037 Tromsø</wicri:noRegion></affiliation></author><author><name sortKey="Quir S, J Ram N" sort="Quir S, J Ram N" uniqKey="Quir S J" first="J Ram N" last="Quir S">J Ram N Quir S</name><affiliation wicri:level="1"><nlm:affiliation>Public Health Directorate, Health and Health Care Services Council, C/ Ciriaco Miguel Virgil no 9, CP 33006 Oviedo, Asturias, Spain.</nlm:affiliation><country xml:lang="fr">Espagne</country><wicri:regionArea>Public Health Directorate, Health and Health Care Services Council, C/ Ciriaco Miguel Virgil no 9, CP 33006 Oviedo, Asturias</wicri:regionArea><wicri:noRegion>Asturias</wicri:noRegion></affiliation></author><author><name sortKey="Ob N Santacana, Mireia" sort="Ob N Santacana, Mireia" uniqKey="Ob N Santacana M" first="Mireia" last="Ob N-Santacana">Mireia Ob N-Santacana</name><affiliation wicri:level="1"><nlm:affiliation>Unit of Nutrition, Environment and Cancer, Cancer Epidemiology Research Program, Bellvitge Biomedical Research Institute (IDIBELL), Catalan Institute of Oncology (ICO), Avda Gran Via 199-203, L'Hospitalet del Llobregat, 08907 Barcelona, Spain.</nlm:affiliation><country xml:lang="fr">Espagne</country><wicri:regionArea>Unit of Nutrition, Environment and Cancer, Cancer Epidemiology Research Program, Bellvitge Biomedical Research Institute (IDIBELL), Catalan Institute of Oncology (ICO), Avda Gran Via 199-203, L'Hospitalet del Llobregat, 08907 Barcelona</wicri:regionArea><placeName><settlement type="city">Barcelone</settlement><region nuts="2" type="region">Catalogne</region></placeName></affiliation></author><author><name sortKey="Molina Montes, Esther" sort="Molina Montes, Esther" uniqKey="Molina Montes E" first="Esther" last="Molina-Montes">Esther Molina-Montes</name><affiliation wicri:level="1"><nlm:affiliation>Escuela Andaluza de Salud Pública, Instituto de Investigación Biosanitaria de Granada (Granada.ibs), Cuesta del Observatorio, 4, Campus Universitario de Cartuja, 18080 Granada, Spain; CIBER de Epidemiología y Salud Pública (CIBERESP), Melchor Fernández Almagro, 3-5, 28029 Madrid, Spain.</nlm:affiliation><country xml:lang="fr">Espagne</country><wicri:regionArea>Escuela Andaluza de Salud Pública, Instituto de Investigación Biosanitaria de Granada (Granada.ibs), Cuesta del Observatorio, 4, Campus Universitario de Cartuja, 18080 Granada, Spain; CIBER de Epidemiología y Salud Pública (CIBERESP), Melchor Fernández Almagro, 3-5, 28029 Madrid</wicri:regionArea><placeName><settlement type="city">Madrid</settlement><region nuts="2" type="region">Communauté de Madrid</region></placeName></affiliation></author><author><name sortKey="Huerta Casta O, Jose Maria" sort="Huerta Casta O, Jose Maria" uniqKey="Huerta Casta O J" first="José María" last="Huerta Casta O">José María Huerta Casta O</name><affiliation wicri:level="1"><nlm:affiliation>CIBER de Epidemiología y Salud Pública (CIBERESP), Melchor Fernández Almagro, 3-5, 28029 Madrid, Spain; Department of Epidemiology, Murcia Regional Health Council, Ronda de Levante 11, 30008 Murcia, Spain.</nlm:affiliation><country xml:lang="fr">Espagne</country><wicri:regionArea>CIBER de Epidemiología y Salud Pública (CIBERESP), Melchor Fernández Almagro, 3-5, 28029 Madrid, Spain; Department of Epidemiology, Murcia Regional Health Council, Ronda de Levante 11, 30008 Murcia</wicri:regionArea><wicri:noRegion>30008 Murcia</wicri:noRegion></affiliation></author><author><name sortKey="Ardanaz, Eva" sort="Ardanaz, Eva" uniqKey="Ardanaz E" first="Eva" last="Ardanaz">Eva Ardanaz</name><affiliation wicri:level="1"><nlm:affiliation>CIBER de Epidemiología y Salud Pública (CIBERESP), Melchor Fernández Almagro, 3-5, 28029 Madrid, Spain; Navarre Public Health Institute, Leyre 15, 31003 Pamplona, Spain.</nlm:affiliation><country xml:lang="fr">Espagne</country><wicri:regionArea>CIBER de Epidemiología y Salud Pública (CIBERESP), Melchor Fernández Almagro, 3-5, 28029 Madrid, Spain; Navarre Public Health Institute, Leyre 15, 31003 Pamplona</wicri:regionArea><wicri:noRegion>31003 Pamplona</wicri:noRegion></affiliation></author><author><name sortKey="Chamosa, Saioa" sort="Chamosa, Saioa" uniqKey="Chamosa S" first="Saioa" last="Chamosa">Saioa Chamosa</name><affiliation wicri:level="1"><nlm:affiliation>Public Health Division of Gipuzkoa, BioDonostia Research Institute, Health Department of Basque Region, Avenida de Navarra, 4-20013 Donostia, San Sebastian, Spain.</nlm:affiliation><country xml:lang="fr">Espagne</country><wicri:regionArea>Public Health Division of Gipuzkoa, BioDonostia Research Institute, Health Department of Basque Region, Avenida de Navarra, 4-20013 Donostia, San Sebastian</wicri:regionArea><wicri:noRegion>San Sebastian</wicri:noRegion></affiliation></author><author><name sortKey="Sonestedt, Emily" sort="Sonestedt, Emily" uniqKey="Sonestedt E" first="Emily" last="Sonestedt">Emily Sonestedt</name><affiliation wicri:level="1"><nlm:affiliation>Department of Clinical Sciences in Malmö, Lund University, 20502 Malmö, Sweden.</nlm:affiliation><country xml:lang="fr">Suède</country><wicri:regionArea>Department of Clinical Sciences in Malmö, Lund University, 20502 Malmö</wicri:regionArea><wicri:noRegion>20502 Malmö</wicri:noRegion></affiliation></author><author><name sortKey="Idahl, Annika" sort="Idahl, Annika" uniqKey="Idahl A" first="Annika" last="Idahl">Annika Idahl</name><affiliation wicri:level="1"><nlm:affiliation>Department of Clinical Sciences, Obstetrics and Gynecology, Umeå University, SE-901 87 Umeå, Sweden; Department of Public Health and Clinical Medicine, Nutritional Research, Umeå University, SE-901 87 Umeå, Sweden.</nlm:affiliation><country xml:lang="fr">Suède</country><wicri:regionArea>Department of Clinical Sciences, Obstetrics and Gynecology, Umeå University, SE-901 87 Umeå, Sweden; Department of Public Health and Clinical Medicine, Nutritional Research, Umeå University, SE-901 87 Umeå</wicri:regionArea><wicri:noRegion>SE-901 87 Umeå</wicri:noRegion></affiliation></author><author><name sortKey="Lundin, Eva" sort="Lundin, Eva" uniqKey="Lundin E" first="Eva" last="Lundin">Eva Lundin</name><affiliation wicri:level="1"><nlm:affiliation>Department of Medical Biosciences, Pathology, Umeå University, SE-901 87 Umeå, Sweden.</nlm:affiliation><country xml:lang="fr">Suède</country><wicri:regionArea>Department of Medical Biosciences, Pathology, Umeå University, SE-901 87 Umeå</wicri:regionArea><wicri:noRegion>SE-901 87 Umeå</wicri:noRegion></affiliation></author><author><name sortKey="Khaw, Kay Tee" sort="Khaw, Kay Tee" uniqKey="Khaw K" first="Kay-Tee" last="Khaw">Kay-Tee Khaw</name><affiliation wicri:level="4"><nlm:affiliation>University of Cambridge, School of Clinical Medicine, Addenbrooke's Hospital, Hills Road, Cambridge CB2 0SP, United Kingdom.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>University of Cambridge, School of Clinical Medicine, Addenbrooke's Hospital, Hills Road, Cambridge CB2 0SP</wicri:regionArea><orgName type="university">Université de Cambridge</orgName><placeName><settlement type="city">Cambridge</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Angleterre de l'Est</region></placeName></affiliation></author><author><name sortKey="Wareham, Nicholas" sort="Wareham, Nicholas" uniqKey="Wareham N" first="Nicholas" last="Wareham">Nicholas Wareham</name><affiliation wicri:level="4"><nlm:affiliation>MRC Epidemiology Unit, University of Cambridge, Institute of Metabolic Science, PO Box 285, Addenbrooke's Hospital, Hills Road, Cambridge CB2 0QQ, United Kingdom.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>MRC Epidemiology Unit, University of Cambridge, Institute of Metabolic Science, PO Box 285, Addenbrooke's Hospital, Hills Road, Cambridge CB2 0QQ</wicri:regionArea><orgName type="university">Université de Cambridge</orgName><placeName><settlement type="city">Cambridge</settlement><region type="country">Angleterre</region><region type="région" nuts="1">Angleterre de l'Est</region></placeName></affiliation></author><author><name sortKey="Travis, Ruth C" sort="Travis, Ruth C" uniqKey="Travis R" first="Ruth C" last="Travis">Ruth C. Travis</name><affiliation wicri:level="4"><nlm:affiliation>Cancer Epidemiology Unit, Nuffield Department of Population Health, University of Oxford, Richard Doll Building, Oxford OX3 7LF, United Kingdom.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Cancer Epidemiology Unit, Nuffield Department of Population Health, University of Oxford, Richard Doll Building, Oxford OX3 7LF</wicri:regionArea><orgName type="university">Université d'Oxford</orgName><placeName><settlement type="city">Oxford</settlement><region type="nation">Angleterre</region><region type="région" nuts="1">Oxfordshire</region></placeName></affiliation></author><author><name sortKey="Rinaldi, Sabina" sort="Rinaldi, Sabina" uniqKey="Rinaldi S" first="Sabina" last="Rinaldi">Sabina Rinaldi</name><affiliation wicri:level="1"><nlm:affiliation>International Agency for Research on Cancer, 150 Cours Albert-Thomas, 69372 Lyon Cedex 08, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>International Agency for Research on Cancer, 150 Cours Albert-Thomas, 69372 Lyon Cedex 08</wicri:regionArea><wicri:noRegion>69372 Lyon Cedex 08</wicri:noRegion><wicri:noRegion>69372 Lyon Cedex 08</wicri:noRegion></affiliation></author><author><name sortKey="Romieu, Isabelle" sort="Romieu, Isabelle" uniqKey="Romieu I" first="Isabelle" last="Romieu">Isabelle Romieu</name><affiliation wicri:level="1"><nlm:affiliation>International Agency for Research on Cancer, 150 Cours Albert-Thomas, 69372 Lyon Cedex 08, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>International Agency for Research on Cancer, 150 Cours Albert-Thomas, 69372 Lyon Cedex 08</wicri:regionArea><wicri:noRegion>69372 Lyon Cedex 08</wicri:noRegion><wicri:noRegion>69372 Lyon Cedex 08</wicri:noRegion></affiliation></author><author><name sortKey="Chajes, Veronique" sort="Chajes, Veronique" uniqKey="Chajes V" first="Veronique" last="Chajes">Veronique Chajes</name><affiliation wicri:level="1"><nlm:affiliation>International Agency for Research on Cancer, 150 Cours Albert-Thomas, 69372 Lyon Cedex 08, France.</nlm:affiliation><country xml:lang="fr">France</country><wicri:regionArea>International Agency for Research on Cancer, 150 Cours Albert-Thomas, 69372 Lyon Cedex 08</wicri:regionArea><wicri:noRegion>69372 Lyon Cedex 08</wicri:noRegion><wicri:noRegion>69372 Lyon Cedex 08</wicri:noRegion></affiliation></author><author><name sortKey="Gunter, Marc J" sort="Gunter, Marc J" uniqKey="Gunter M" first="Marc J" last="Gunter">Marc J. Gunter</name><affiliation wicri:level="1"><nlm:affiliation>Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London, Norfolk Place, London W2 1PG, United Kingdom.</nlm:affiliation><country xml:lang="fr">Royaume-Uni</country><wicri:regionArea>Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London, Norfolk Place, London W2 1PG</wicri:regionArea><wicri:noRegion>London W2 1PG</wicri:noRegion></affiliation></author></analytic><series><title level="j">Cancer epidemiology</title><idno type="eISSN">1877-783X</idno><imprint><date when="2014" type="published">2014</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Adult</term><term>Dietary Fats (administration & dosage)</term><term>Dietary Fats (adverse effects)</term><term>Dietary Fats, Unsaturated (administration & dosage)</term><term>Dietary Fats, Unsaturated (adverse effects)</term><term>Female</term><term>Follow-Up Studies</term><term>Humans</term><term>Middle Aged</term><term>Multivariate Analysis</term><term>Neoplasms, Glandular and Epithelial (epidemiology)</term><term>Neoplasms, Glandular and Epithelial (etiology)</term><term>Ovarian Neoplasms (epidemiology)</term><term>Ovarian Neoplasms (etiology)</term><term>Proportional Hazards Models</term><term>Prospective Studies</term><term>Risk</term></keywords><keywords scheme="KwdFr" xml:lang="fr"><term>Adulte</term><term>Adulte d'âge moyen</term><term>Analyse multivariée</term><term>Femelle</term><term>Humains</term><term>Matières grasses alimentaires (administration et posologie)</term><term>Matières grasses alimentaires (effets indésirables)</term><term>Matières grasses alimentaires insaturées (administration et posologie)</term><term>Matières grasses alimentaires insaturées (effets indésirables)</term><term>Modèles de hasards proportionnels</term><term>Risque</term><term>Tumeurs de l'ovaire (épidémiologie)</term><term>Tumeurs de l'ovaire (étiologie)</term><term>Tumeurs épithéliales épidermoïdes et glandulaires (épidémiologie)</term><term>Tumeurs épithéliales épidermoïdes et glandulaires (étiologie)</term><term>Études de suivi</term><term>Études prospectives</term></keywords><keywords scheme="MESH" type="chemical" qualifier="administration & dosage" xml:lang="en"><term>Dietary Fats</term><term>Dietary Fats, Unsaturated</term></keywords><keywords scheme="MESH" type="chemical" qualifier="adverse effects" xml:lang="en"><term>Dietary Fats</term><term>Dietary Fats, Unsaturated</term></keywords><keywords scheme="MESH" qualifier="administration et posologie" xml:lang="fr"><term>Matières grasses alimentaires</term><term>Matières grasses alimentaires insaturées</term></keywords><keywords scheme="MESH" qualifier="effets indésirables" xml:lang="fr"><term>Matières grasses alimentaires</term><term>Matières grasses alimentaires insaturées</term></keywords><keywords scheme="MESH" qualifier="epidemiology" xml:lang="en"><term>Neoplasms, Glandular and Epithelial</term><term>Ovarian Neoplasms</term></keywords><keywords scheme="MESH" qualifier="etiology" xml:lang="en"><term>Neoplasms, Glandular and Epithelial</term><term>Ovarian Neoplasms</term></keywords><keywords scheme="MESH" qualifier="épidémiologie" xml:lang="fr"><term>Tumeurs de l'ovaire</term><term>Tumeurs épithéliales épidermoïdes et glandulaires</term></keywords><keywords scheme="MESH" qualifier="étiologie" xml:lang="fr"><term>Tumeurs de l'ovaire</term><term>Tumeurs épithéliales épidermoïdes et glandulaires</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Adult</term><term>Female</term><term>Follow-Up Studies</term><term>Humans</term><term>Middle Aged</term><term>Multivariate Analysis</term><term>Proportional Hazards Models</term><term>Prospective Studies</term><term>Risk</term></keywords><keywords scheme="MESH" xml:lang="fr"><term>Adulte</term><term>Adulte d'âge moyen</term><term>Analyse multivariée</term><term>Femelle</term><term>Humains</term><term>Modèles de hasards proportionnels</term><term>Risque</term><term>Études de suivi</term><term>Études prospectives</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">There are inconsistent and limited data available to assess the relationship between fat intake and risk of epithelial ovarian cancer (EOC). We examined the consumption of total fat, fat sources and fat subtypes in relation to risk of EOC and its major histologic subtypes in the European Prospective Investigation into Cancer and Nutrition which includes incident invasive (n=1095) and borderline (n=96) EOC. Cox proportional hazards regression was used to estimate hazard ratios (HRs) and 95% confidence intervals (CIs). In multivariate models, we observed no association with consumption of total fat, animal or plant fat, saturated fat, cholesterol, monounsaturated fat, or fatty fish and risk of invasive EOC. There was, however, an increased risk of invasive EOC in the highest category of intake (Quartile 4 vs. Quartile 1) of polyunsaturated fat (HR=1.22, 95% CI=1.02-1.48, P(trend)=0.02). We did not observe heterogeneity in the risk associations in comparisons of serous and endometrioid histologic subtypes. This study does not support an etiological role for total fat intake in relation to EOC risk; however, based on observations of a positive association between intake of polyunsaturated fat and invasive EOC risk in the current and previous studies, this fat subtype warrants further investigation to determine its potential role in EOC development.</div></front></TEI><affiliations><list><country><li>Allemagne</li><li>Australie</li><li>Danemark</li><li>Espagne</li><li>Finlande</li><li>France</li><li>Grèce</li><li>Italie</li><li>Norvège</li><li>Pays-Bas</li><li>Royaume-Uni</li><li>Suède</li><li>États-Unis</li></country><region><li>Angleterre</li><li>Angleterre de l'Est</li><li>Bade-Wurtemberg</li><li>Catalogne</li><li>Communauté de Madrid</li><li>District de Karlsruhe</li><li>Massachusetts</li><li>Oxfordshire</li><li>Piémont</li><li>Victoria (État)</li><li>Østlandet</li></region><settlement><li>Barcelone</li><li>Cambridge</li><li>Heidelberg</li><li>Madrid</li><li>Melbourne</li><li>Oslo</li><li>Oxford</li><li>Turin</li></settlement><orgName><li>Université d'Oxford</li><li>Université de Cambridge</li><li>Université de Melbourne</li></orgName></list><tree><country name="Royaume-Uni"><noRegion><name sortKey="Merritt, Melissa A" sort="Merritt, Melissa A" uniqKey="Merritt M" first="Melissa A" last="Merritt">Melissa A. Merritt</name></noRegion><name sortKey="Gunter, Marc J" sort="Gunter, Marc J" uniqKey="Gunter M" first="Marc J" last="Gunter">Marc J. Gunter</name><name sortKey="Khaw, Kay Tee" sort="Khaw, Kay Tee" uniqKey="Khaw K" first="Kay-Tee" last="Khaw">Kay-Tee Khaw</name><name sortKey="Riboli, Elio" sort="Riboli, Elio" uniqKey="Riboli E" first="Elio" last="Riboli">Elio Riboli</name><name sortKey="Travis, Ruth C" sort="Travis, Ruth C" uniqKey="Travis R" first="Ruth C" last="Travis">Ruth C. Travis</name><name sortKey="Tsilidis, Konstantinos K" sort="Tsilidis, Konstantinos K" uniqKey="Tsilidis K" first="Konstantinos K" last="Tsilidis">Konstantinos K. Tsilidis</name><name sortKey="Wareham, Nicholas" sort="Wareham, Nicholas" uniqKey="Wareham N" first="Nicholas" last="Wareham">Nicholas Wareham</name></country><country name="Finlande"><noRegion><name sortKey="Weiderpass, Elisabete" sort="Weiderpass, Elisabete" uniqKey="Weiderpass E" first="Elisabete" last="Weiderpass">Elisabete Weiderpass</name></noRegion></country><country name="Danemark"><noRegion><name sortKey="Overvad, Kim" sort="Overvad, Kim" uniqKey="Overvad K" first="Kim" last="Overvad">Kim Overvad</name></noRegion><name sortKey="Hansen, Louise" sort="Hansen, Louise" uniqKey="Hansen L" first="Louise" last="Hansen">Louise Hansen</name><name sortKey="Tj Nneland, Anne" sort="Tj Nneland, Anne" uniqKey="Tj Nneland A" first="Anne" last="Tj Nneland">Anne Tj Nneland</name></country><country name="France"><noRegion><name sortKey="Dossus, Laure" sort="Dossus, Laure" uniqKey="Dossus L" first="Laure" last="Dossus">Laure Dossus</name></noRegion><name sortKey="Chajes, Veronique" sort="Chajes, Veronique" uniqKey="Chajes V" first="Veronique" last="Chajes">Veronique Chajes</name><name sortKey="Fagherazzi, Guy" sort="Fagherazzi, Guy" uniqKey="Fagherazzi G" first="Guy" last="Fagherazzi">Guy Fagherazzi</name><name sortKey="Rinaldi, Sabina" sort="Rinaldi, Sabina" uniqKey="Rinaldi S" first="Sabina" last="Rinaldi">Sabina Rinaldi</name><name sortKey="Romieu, Isabelle" sort="Romieu, Isabelle" uniqKey="Romieu I" first="Isabelle" last="Romieu">Isabelle Romieu</name></country><country name="Australie"><region name="Victoria (État)"><name sortKey="Baglietto, Laura" sort="Baglietto, Laura" uniqKey="Baglietto L" first="Laura" last="Baglietto">Laura Baglietto</name></region></country><country name="Allemagne"><region name="Bade-Wurtemberg"><name sortKey="Fortner, Renee T" sort="Fortner, Renee T" uniqKey="Fortner R" first="Renée T" last="Fortner">Renée T. Fortner</name></region><name sortKey="Boeing, Heiner" sort="Boeing, Heiner" uniqKey="Boeing H" first="Heiner" last="Boeing">Heiner Boeing</name><name sortKey="Ose, Jennifer" sort="Ose, Jennifer" uniqKey="Ose J" first="Jennifer" last="Ose">Jennifer Ose</name><name sortKey="Steffen, Annika" sort="Steffen, Annika" uniqKey="Steffen A" first="Annika" last="Steffen">Annika Steffen</name></country><country name="Grèce"><noRegion><name sortKey="Trichopoulou, Antonia" sort="Trichopoulou, Antonia" uniqKey="Trichopoulou A" first="Antonia" last="Trichopoulou">Antonia Trichopoulou</name></noRegion><name sortKey="Lagiou, Pagona" sort="Lagiou, Pagona" uniqKey="Lagiou P" first="Pagona" last="Lagiou">Pagona Lagiou</name></country><country name="États-Unis"><region name="Massachusetts"><name sortKey="Trichopoulos, Dimitrios" sort="Trichopoulos, Dimitrios" uniqKey="Trichopoulos D" first="Dimitrios" last="Trichopoulos">Dimitrios Trichopoulos</name></region></country><country name="Italie"><noRegion><name sortKey="Masala, Giovanna" sort="Masala, Giovanna" uniqKey="Masala G" first="Giovanna" last="Masala">Giovanna Masala</name></noRegion><name sortKey="Mattiello, Amalia" sort="Mattiello, Amalia" uniqKey="Mattiello A" first="Amalia" last="Mattiello">Amalia Mattiello</name><name sortKey="Sacerdote, Carlotta" sort="Sacerdote, Carlotta" uniqKey="Sacerdote C" first="Carlotta" last="Sacerdote">Carlotta Sacerdote</name><name sortKey="Sieri, Sabina" sort="Sieri, Sabina" uniqKey="Sieri S" first="Sabina" last="Sieri">Sabina Sieri</name><name sortKey="Tumino, Rosario" sort="Tumino, Rosario" uniqKey="Tumino R" first="Rosario" last="Tumino">Rosario Tumino</name></country><country name="Pays-Bas"><noRegion><name sortKey="Bueno De Mesquita, H B As" sort="Bueno De Mesquita, H B As" uniqKey="Bueno De Mesquita H" first="H B As" last="Bueno-De-Mesquita">H B As Bueno-De-Mesquita</name></noRegion><name sortKey="Onland Moret, N Charlotte" sort="Onland Moret, N Charlotte" uniqKey="Onland Moret N" first="N Charlotte" last="Onland-Moret">N Charlotte Onland-Moret</name><name sortKey="Peeters, Petra H" sort="Peeters, Petra H" uniqKey="Peeters P" first="Petra H" last="Peeters">Petra H. Peeters</name></country><country name="Norvège"><region name="Østlandet"><name sortKey="Hjart Ker, Anette" sort="Hjart Ker, Anette" uniqKey="Hjart Ker A" first="Anette" last="Hjart Ker">Anette Hjart Ker</name></region><name sortKey="Gram, Inger Torhild" sort="Gram, Inger Torhild" uniqKey="Gram I" first="Inger Torhild" last="Gram">Inger Torhild Gram</name></country><country name="Espagne"><noRegion><name sortKey="Quir S, J Ram N" sort="Quir S, J Ram N" uniqKey="Quir S J" first="J Ram N" last="Quir S">J Ram N Quir S</name></noRegion><name sortKey="Ardanaz, Eva" sort="Ardanaz, Eva" uniqKey="Ardanaz E" first="Eva" last="Ardanaz">Eva Ardanaz</name><name sortKey="Chamosa, Saioa" sort="Chamosa, Saioa" uniqKey="Chamosa S" first="Saioa" last="Chamosa">Saioa Chamosa</name><name sortKey="Huerta Casta O, Jose Maria" sort="Huerta Casta O, Jose Maria" uniqKey="Huerta Casta O J" first="José María" last="Huerta Casta O">José María Huerta Casta O</name><name sortKey="Molina Montes, Esther" sort="Molina Montes, Esther" uniqKey="Molina Montes E" first="Esther" last="Molina-Montes">Esther Molina-Montes</name><name sortKey="Ob N Santacana, Mireia" sort="Ob N Santacana, Mireia" uniqKey="Ob N Santacana M" first="Mireia" last="Ob N-Santacana">Mireia Ob N-Santacana</name></country><country name="Suède"><noRegion><name sortKey="Sonestedt, Emily" sort="Sonestedt, Emily" uniqKey="Sonestedt E" first="Emily" last="Sonestedt">Emily Sonestedt</name></noRegion><name sortKey="Idahl, Annika" sort="Idahl, Annika" uniqKey="Idahl A" first="Annika" last="Idahl">Annika Idahl</name><name sortKey="Lundin, Eva" sort="Lundin, Eva" uniqKey="Lundin E" first="Eva" last="Lundin">Eva Lundin</name></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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